Safran B6 gummies contain a high dose of 40 mg of pure saffron extract per gummy. They are recommended for periods of increased stress, fatigue, or emotional tension that may be difficult to manage.
Combined with vitamin B6, they support mental balance, help reduce nervousness, and contribute to a more stable mood, providing relief during times of emotional strain or everyday stress.
DOSAGE
Children (from 4 years old): 1 gummy per day if under 30 kg, 2 gummies per day if over 30 kg.
Adults: 2 gummies per day.
Store in a dry place, away from light.
CONTRAINDICATIONS
Not recommended for children under 4 years old, pregnant or breastfeeding women, or individuals taking antidepressant medication.
DELIVERY
Estimated delivery time is 5 to 7 working days.
SAFFRON B6 GUMMIES
Regular price
£21.90
Sale price
£21.90
Regular price
How science powers our gummies
CLINICAL STUDIES
Saffron, known by its scientific name Crocus sativus, has been valued for millennia for its multiple therapeutic benefits. Recent clinical studies have highlighted its antioxidant and anti-inflammatory properties, as well as its positive impact on mood and mental health, making it a promising candidate for supporting symptoms of depression and anxiety.
Effect on mood and well-being
A double-blind, placebo-controlled study found that supplementing with 30 mg of saffron extract for 8 weeks improved emotional well-being in healthy adults experiencing subclinical feelings of low mood, anxiety, and/or stress. The same study observed that saffron extract reduced depression scores and enhanced social relationships by the end of the trial, suggesting an improvement in subclinical depressive symptoms in healthy individuals (Jackson et al., 2021).
Antidepressant and anxiolytic properties
Research suggests that saffron has effects similar to current antidepressant medications but with fewer reported side effects. These benefits are believed to come from saffron’s active compounds, primarily crocin and safranal (Shafiee et al., 2018).
Reduction of depression and anxiety symptoms
A meta-analysis confirmed that saffron supplementation leads to a significant reduction in scores on the Beck Depression Inventory (BDI), the Beck Anxiety Inventory (BAI), and the Pittsburgh Sleep Quality Index (PSQI), without affecting C-reactive protein (CRP) levels. This suggests a decrease in depression and anxiety symptoms without impacting systemic inflammation (Ghaderi et al., 2020). These clinical studies indicate that saffron could be an effective intervention for managing symptoms of depression and anxiety, offering a natural alternative to conventional treatments. Additionally, vitamin B6, essential for the optimal functioning of the nervous and immune systems, helps reduce fatigue and supports mood by contributing to serotonin synthesis. Together, saffron and vitamin B6 form a powerful duo to support mental health and overall well-being.
ACTIVE INGREDIENTS
The most concentrated saffron on the market
Our saffron, made exclusively from Sargol (the richest red tip in active compounds and aroma), is the most concentrated extract of crocins and safranal available. Classified as 100% red and ranked in Category 1 according to international standards, our saffron guarantees superior purity and potency, reflecting our commitment to exceptional quality and total customer satisfaction.
Geographical origin and history
Grown in the fertile lands of northeastern Iran, our saffron benefits from a centuries-old agricultural tradition and is harvested using traditional methods that ensure its premium quality. Hand-harvested at sunrise in the Khorasan province, this careful process is essential to maintaining the spice’s superior quality and high concentration of active compounds.
A rigorous 10-step analysis process
Our commitment to quality is reflected in a strict 10-step analysis protocol, from traditional hand-picking to in-depth laboratory testing. This process guarantees the purity, potency, and integrity of our saffron, ensuring consistent and verifiable quality.
Impact on well-being and health
With its rich bioactive profile and our meticulous selection process, our saffron plays a significant role in mental health and overall well-being, demonstrating the latest scientific advances in the field of phytotherapy.
Children (from 4 years old): 1 gummy per day if under 30 kg, 2 gummies per day if over 30 kg.
Adults: 2 gummies per day.
Store in a dry place, away from light.
Contraindications
Not recommended for children under 4 years old, pregnant or breastfeeding women, or individuals taking antidepressant medication.
SCIENCE
Neurobiological foundations of mood
Mood regulation is a neurobiological process involving brain structures such as the amygdala (emotion processing) and the prefrontal cortex (regulation of emotional responses and decision-making). Neurotransmitters like serotonin (often referred to as the "happiness hormone") and dopamine, which is linked to the brain’s reward system, play a key role in mood modulation. A disruption in these systems, often triggered by stress or psychological disorders, can lead to a persistent sense of discomfort, sadness, and apathy.
Dysphoria and neurotransmitter imbalance
Dysphoria, characterised by a consistently disturbed mood, is closely linked to imbalances in these neurotransmitters. Serotonin directly influences well-being and satisfaction, while dopamine affects motivation and the perception of pleasure. Prolonged irregularities in neurotransmitter signalling can reduce emotional resilience, impair stress management, and lower engagement in daily activities.
The influence of circadian rhythms on mood
Circadian rhythms, or the body’s internal clock, regulate sleep cycles, wakefulness, mood, and behaviour, playing a crucial role in mental health. These rhythms are controlled by the suprachiasmatic nucleus in the hypothalamus, which synchronises our internal clock with the day-night cycle based on ambient light. Disruptions such as shift work, jet lag, or stress can desynchronise these rhythms.
Vitamin B6 and saffron in mood regulation
Vitamin B6, essential for the synthesis of serotonin and dopamine, is key to maintaining mood balance, and a deficiency can disrupt this equilibrium. Saffron has also been shown to have positive effects on the serotonergic system and may help alleviate symptoms of dysphoria, enhancing mood and contributing to overall well-being.
References
Wever, R. A. (1979). The Circadian System of Man: Results of Experiments under Temporal Isolation. Springer. Panda, S. (2018). The Circadian Code. Penguin Random House. Bernard, S., Gonze, D., Cajavec, B., Herzel, H., & Kramer, A. (2007). Synchronization-induced rhythmicity of circadian oscillators in the suprachiasmatic nucleus. PLoS Computational Biology, 3(4), e68. Borbély, A. A., Daan, S., Wirz-Justice, A., & Deboer, T. (2016). The two-process model of sleep regulation: a reappraisal. Journal of Sleep Research, 25(2), 131-143. INSERM. (2017).Sleep: Shedding Light on Our Nocturnal Activity.
BENEFITS
Saffron extract has been the subject of extensive clinical research aimed at uncovering its quantifiable therapeutic effects, particularly in the fields of psychiatry and neuroendocrinology. It is being studied for its potential to modulate depressive symptoms, improve sleep quality, and influence neurobiological responses to stress.Supports the management of depressive symptoms
Saffron extract has been clinically validated for its ability to alleviate symptoms of depression. In a study by Marx et al. (2019), participants receiving saffron experienced a significant reduction in depressive symptoms, suggesting a positive effect on mental health and mood regulation.
Enhances sleep quality
Saffron supplementation has been shown to improve sleep quality in adults, as demonstrated in a study by Lopresti et al. (2021). This effect may be linked to saffron’s influence on neurotransmitters associated with sleep cycles and relaxation.
Improves well-being and mood
Saffron appears to play a role in enhancing overall well-being, according to a study by Jackson et al. (2021). Participants who consumed saffron reported an increase in well-being and a reduction in stress symptoms, contributing to a better overall quality of life.
Regulates stress response and cortisol levels
Research by Pouchieu et al. (2023) suggests that saffron may help regulate both the biological and psychological response to stress. Findings indicate that saffron may influence cortisol levels, the primary stress hormone, which could have positive implications for managing chronic stress.
CLINICAL STUDIES
ACTIVE INGREDIENTS
COMPOSITION
SCIENCE
BENEFITS
Saffron, known by its scientific name Crocus sativus, has been valued for millennia for its multiple therapeutic benefits. Recent clinical studies have highlighted its antioxidant and anti-inflammatory properties, as well as its positive impact on mood and mental health, making it a promising candidate for supporting symptoms of depression and anxiety.
Effect on mood and well-being
A double-blind, placebo-controlled study found that supplementing with 30 mg of saffron extract for 8 weeks improved emotional well-being in healthy adults experiencing subclinical feelings of low mood, anxiety, and/or stress. The same study observed that saffron extract reduced depression scores and enhanced social relationships by the end of the trial, suggesting an improvement in subclinical depressive symptoms in healthy individuals (Jackson et al., 2021).
Antidepressant and anxiolytic properties
Research suggests that saffron has effects similar to current antidepressant medications but with fewer reported side effects. These benefits are believed to come from saffron’s active compounds, primarily crocin and safranal (Shafiee et al., 2018).
Reduction of depression and anxiety symptoms
A meta-analysis confirmed that saffron supplementation leads to a significant reduction in scores on the Beck Depression Inventory (BDI), the Beck Anxiety Inventory (BAI), and the Pittsburgh Sleep Quality Index (PSQI), without affecting C-reactive protein (CRP) levels. This suggests a decrease in depression and anxiety symptoms without impacting systemic inflammation (Ghaderi et al., 2020). These clinical studies indicate that saffron could be an effective intervention for managing symptoms of depression and anxiety, offering a natural alternative to conventional treatments. Additionally, vitamin B6, essential for the optimal functioning of the nervous and immune systems, helps reduce fatigue and supports mood by contributing to serotonin synthesis. Together, saffron and vitamin B6 form a powerful duo to support mental health and overall well-being.
The most concentrated saffron on the market
Our saffron, made exclusively from Sargol (the richest red tip in active compounds and aroma), is the most concentrated extract of crocins and safranal available. Classified as 100% red and ranked in Category 1 according to international standards, our saffron guarantees superior purity and potency, reflecting our commitment to exceptional quality and total customer satisfaction.
Geographical origin and history
Grown in the fertile lands of northeastern Iran, our saffron benefits from a centuries-old agricultural tradition and is harvested using traditional methods that ensure its premium quality. Hand-harvested at sunrise in the Khorasan province, this careful process is essential to maintaining the spice’s superior quality and high concentration of active compounds.
A rigorous 10-step analysis process
Our commitment to quality is reflected in a strict 10-step analysis protocol, from traditional hand-picking to in-depth laboratory testing. This process guarantees the purity, potency, and integrity of our saffron, ensuring consistent and verifiable quality.
Impact on well-being and health
With its rich bioactive profile and our meticulous selection process, our saffron plays a significant role in mental health and overall well-being, demonstrating the latest scientific advances in the field of phytotherapy.
Children (from 4 years old): 1 gummy per day if under 30 kg, 2 gummies per day if over 30 kg.
Adults: 2 gummies per day.
Store in a dry place, away from light.
Contraindications
Not recommended for children under 4 years old, pregnant or breastfeeding women, or individuals taking antidepressant medication.
Neurobiological foundations of mood
Mood regulation is a neurobiological process involving brain structures such as the amygdala (emotion processing) and the prefrontal cortex (regulation of emotional responses and decision-making). Neurotransmitters like serotonin (often referred to as the "happiness hormone") and dopamine, which is linked to the brain’s reward system, play a key role in mood modulation. A disruption in these systems, often triggered by stress or psychological disorders, can lead to a persistent sense of discomfort, sadness, and apathy.
Dysphoria and neurotransmitter imbalance
Dysphoria, characterised by a consistently disturbed mood, is closely linked to imbalances in these neurotransmitters. Serotonin directly influences well-being and satisfaction, while dopamine affects motivation and the perception of pleasure. Prolonged irregularities in neurotransmitter signalling can reduce emotional resilience, impair stress management, and lower engagement in daily activities.
The influence of circadian rhythms on mood
Circadian rhythms, or the body’s internal clock, regulate sleep cycles, wakefulness, mood, and behaviour, playing a crucial role in mental health. These rhythms are controlled by the suprachiasmatic nucleus in the hypothalamus, which synchronises our internal clock with the day-night cycle based on ambient light. Disruptions such as shift work, jet lag, or stress can desynchronise these rhythms.
Vitamin B6 and saffron in mood regulation
Vitamin B6, essential for the synthesis of serotonin and dopamine, is key to maintaining mood balance, and a deficiency can disrupt this equilibrium. Saffron has also been shown to have positive effects on the serotonergic system and may help alleviate symptoms of dysphoria, enhancing mood and contributing to overall well-being.
References
Wever, R. A. (1979). The Circadian System of Man: Results of Experiments under Temporal Isolation. Springer. Panda, S. (2018). The Circadian Code. Penguin Random House. Bernard, S., Gonze, D., Cajavec, B., Herzel, H., & Kramer, A. (2007). Synchronization-induced rhythmicity of circadian oscillators in the suprachiasmatic nucleus. PLoS Computational Biology, 3(4), e68. Borbély, A. A., Daan, S., Wirz-Justice, A., & Deboer, T. (2016). The two-process model of sleep regulation: a reappraisal. Journal of Sleep Research, 25(2), 131-143. INSERM. (2017).Sleep: Shedding Light on Our Nocturnal Activity.
Saffron extract has been the subject of extensive clinical research aimed at uncovering its quantifiable therapeutic effects, particularly in the fields of psychiatry and neuroendocrinology. It is being studied for its potential to modulate depressive symptoms, improve sleep quality, and influence neurobiological responses to stress.Supports the management of depressive symptoms
Saffron extract has been clinically validated for its ability to alleviate symptoms of depression. In a study by Marx et al. (2019), participants receiving saffron experienced a significant reduction in depressive symptoms, suggesting a positive effect on mental health and mood regulation.
Enhances sleep quality
Saffron supplementation has been shown to improve sleep quality in adults, as demonstrated in a study by Lopresti et al. (2021). This effect may be linked to saffron’s influence on neurotransmitters associated with sleep cycles and relaxation.
Improves well-being and mood
Saffron appears to play a role in enhancing overall well-being, according to a study by Jackson et al. (2021). Participants who consumed saffron reported an increase in well-being and a reduction in stress symptoms, contributing to a better overall quality of life.
Regulates stress response and cortisol levels
Research by Pouchieu et al. (2023) suggests that saffron may help regulate both the biological and psychological response to stress. Findings indicate that saffron may influence cortisol levels, the primary stress hormone, which could have positive implications for managing chronic stress.
I tried these dummies on a plane ride a few years ago. It took me a while to find them as you don’t sell in the UK. They are the best I have found. Please market them to the UK!
F
Flora J.
Mood cure
Easy to take and effective treatment, after 3 weeks, my mood has improved. Coupled with a magnesium treatment, I feel more clear-headed and less down.
S
Stéphanie B.
Good
My son has been taking this for 15 days (ADHD) for the moment I am waiting to see the result.
M
Marina F.
Visible effects after 3 months
Very satisfied with this product, effects noticed after 10-15 days, feeling more relaxed and rested. Less nervousness.
N
Nassima D.
Perfect
I feel better but the taste is weird.
F
Florencia F.
Satisfied
Fast delivery. The gummies taste good and have a pleasant, non-sticky texture (better than competitors and more affordable). I have the impression that it is effective for me and my daughter who sleeps better.
J
Jennifer L.
Perfect
My son, who shows signs of ADHD, is much more focused at school since he took them. I recommend
A
Aurélie L.
Perfect
The taste is very appreciated by my 12 year old daughter (although very picky). And the positive effects on his mood were felt after 10 days. THANKS !
B
Bélinda G.
Mium
Good morning
I find that my daughter is less sad and more cheerful.
She pulled up her grades.
1 month since she started.
So I'm happy thank you
A
Amandine S.
Convinced
I've been ordering gummies for several months and after a forced break I saw the difference with my two children. Improved sleep and easier emotion management.
What ingredients are in Mium Lab's Saffron B6 gummies?
Our Saffron B6 gummies contain saffron extract, with the highest concentration of crocins and safranal available on the market.
Saffron, used for thousands of years for its medicinal benefits, is combined here with vitamin B6 to maximise its positive effects on mood and mental well-being. Together, they work in synergy to reduce stress, promote a positive mood, and support normal neurological function.
Which vitamins are present in the sugar-free Saffron B6 gummies?
Our Saffron B6 gummies are formulated with vitamin B6, essential for the optimal function of the nervous and immune systems. Vitamin B6 helps reduce fatigue and improve mood by supporting the synthesis of serotonin.
From what age can Mium Lab's Saffron B6 gummies be taken?
Our Saffron B6 gummies can be taken from the age of 4.
What are the health and well-being benefits of Saffron B6 gummies?
Many studies have shown that saffron has antioxidant properties, anti-inflammatory effects, and can have positive effects on mood and mental health.
Why follow a course of Mium Lab's Saffron B6 gummies for emotional balance?
If you are experiencing periods of low mood or are looking to improve your overall emotional well-being, Mium Lab's saffron and vitamin B6 gummies is a natural solution that helps reduce stress and improve mood while playing a key role in mental health and the prevention of mild to moderate depression.
What are the contraindications for sugar-free Saffron B6 gummies (pregnancy, medication)?
Not recommended for pregnant or breast-feeding women, or for people taking antidepressants.
Why choose Mium Lab's Saffron B6 gummies over other supplements?
Our Saffron B6 gummies currently contain the highest dosage on the market, with 40mg of saffron per 2 gummies, compared to an average of around 30mg.
Our saffron is sourced from the precious red part of the flower, known as Sargol, a symbol of premium saffron quality. Our 100% red saffron is classified as Category 1, the highest distinction awarded by international standards, such as those set by the International Organization for Standardization (ISO). This classification is based on strict quality criteria, including colour intensity (crocin), characteristic aroma (safranal), and specific taste (picrocrocin). Category 1 signifies the highest levels of these bioactive compounds, ensuring superior quality in terms of colour, aroma, and taste.
The saffron in Mium Lab's Saffron B6 gummies works specifically to support mood, stress, skin, sleep, and premenstrual syndrome.
Our saffron, sourced from organic farming, is also certified vegan, kosher, and halal.
What is the ideal duration for a course of sugar-free Saffron B6 gummies?
The first effects of the Saffron B6 course can be felt as early as three weeks. However, the course can be extended up to three months and renewed to maintain or further improve the results achieved.
Are Saffron B6 gummies effective for mood disorders and attention deficit (ADHD) in children?
Yes, studies show that saffron can be beneficial for children experiencing mood disorders or ADHD. It naturally helps improve concentration and reduce anxiety, with no notable side effects. In short, saffron is a natural and safe solution to support mood and focus in children.
